A recent study from the Olsen group at University of Copenhagen, has capitalized on the recent developments in both high sensitivity instrumentation and sample preparation methods to perform single-cell pSILAC experiments providing functional information on protein turnover at the single-cell level.
A single blood test can now reveal thousands of proteins, offering unprecedented insights into early diagnosis, personalized medicine, and health monitoring. The driving force behind this progress? Advances in LC-MS technology.
Plasma proteomics, key in biomarker discovery, faces challenges. Evosep One simplifies workflow, enhances reproducibility, reduces costs, and speeds up analysis with automated Evotip loading, revolutionizing research potential and clinical outcomes.
Biomarker tests have become an important tool in clinical diagnostics. The PSA test evaluates the risk for prostate cancer, and inflammatory and myocardial panels save lives when performed fast enough. Still biomarkers, especially protein biomarkers, are not yet used to their full potential. While novel approaches employ mass spectrometry instead of immunoassay detection, one bottleneck remains: the need for robust, fast, and efficient sample preparation.
