In a collaboration with Thermo Fisher Scientific, the Olsen Group and Novo Nordisk Foundation Center for Protein Research have described the new Thermo Scientific™ Orbitrap Exploris™ 480 mass spectrometer for high-throughput analyses with short gradients using the Evosep One.
The need for scalable methods for functional annotation of phosphotyrosine sites has led the Olsen group, Novo Nordisk Foundation Center for Protein Research in Copenhagen, to develop a new mass spectrometry-based workflow for high-throughput analyses. In a recent study, they implemented this new workflow used to describe how cancer mutations close to tyrosine phosphorylation sites in the EGF receptor rewire signaling pathways by switching protein interactors.
A collaboration between Mathias Mann’s lab and the Jesper Olsen Group together with Head of Applications at Evosep, Nicholai Bache, has just submitted key results to MCP. Their research shows how to further integrate MS-based proteomics into biomedical research and clinical settings while ensuring high throughput and robustness using the Evosep One.
